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Herein we report a thiol-labile cysteine protecting group based on an unsaturated pyridazinedione (PD) scaffold. We establish compatibility of the PD in conventional solid phase peptide synthesis (SPPS), showcasing this...doi:10.1039/d1cc03802h pmid:34747956 fatcat:z37ufmuejfcgbcz7iz5pvy3xga