NMR spectroscopic properties of furo[2′,3′:4,5]pyrrolo[1,2-d][1,2,4]triazine derivatives

Ivana Zemanová, Renata Gašparová
2017 Nova Biotechnologica et Chimica  
The 1 H and 13 C NMR spectroscopic properties of a series of furo [2',3':4,5]pyrrolo [1,2-d][1,2,4]triazin-8(7H)-ones and -thiones were investigated. The influence of various electron donating as well as electron withdrawing substituents at C-5 or N-7 on 1 H NMR chemical shifts as well as 13 C chemical shifts at C8 were observed. The 5-chloromethyl group had a little influence on the chemical shift of H-7 proton and the 8-thione group causes deshielding of H-7 as well as H-5 protons in comparison with the C-8 carbonyl group.
doi:10.1515/nbec-2017-0020 fatcat:hr3kyacnkbb27fwe4djd7s6dem