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Morphological changes in gray matter volume correlate with catechol-O-methyl transferase gene Val158Met polymorphism in first-episode treatment-naïve patients with schizophrenia
2015
Neuroscience Bulletin
The catechol-O-methyltransferase (COMT) gene is a schizophrenia susceptibility gene. A common functional polymorphism of this gene, Val158/158Met, has been proposed to infl uence gray matter volume (GMV). However, the effects of this polymorphism on cortical thickness/ surface area in schizophrenic patients are less clear. In this study, we explored the relationship between the Val158Met polymorphism of the COMT gene and the GMV/ cortical thickness/cortical surface area in 150 firstepisode
doi:10.1007/s12264-014-1491-7
pmid:25564193
pmcid:PMC5562642
fatcat:tzqg5fiplbhzhhlkxwfc3q5vlm