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Modulation of electrocorticographic seizure features predicts response to closed-loop brain stimulation
[article]
2018
bioRxiv
pre-print
Why does closed-loop invasive brain stimulation improve seizure control in some patients with epilepsy, but not others? The RNS System, the only FDA-approved bi-directional brain-computer interface, has been shown to improve seizure control in patients with refractory epilepsy, although the mechanisms behind this success are undefined. We analyzed recordings from the RNS System and discovered two main categories of electrophysiological signatures of stimulation-induced modulation of the seizure
doi:10.1101/408567
fatcat:4hampfdod5ah7imphiqhmnfuii