The aim of this study was to evaluate the effects of 72-h sleep deprivation on normal daily activities (work, family, and sports), and to investigate whether sleep can be chronically reduced without dangerous consequences. Methods: The participant in this study was an adult male (age 41 years; mass 69 kg; height 173 cm). During the 72 h, data were collected every 6 h, involving a baseline (pre-deprivation). We monitored various parameters: Oxidative Stress (D-Rom and Bap test), Psychological

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... ponses (test POMS and Measure of Global Stress), Metabolic expenditure (kJ) using a metabolic holter, EEG records, Cortisol, and Catecholamines level. Results: An interesting result was observed in the post-test phase, when a brief moment of deep sleep and total absence of a very deep sleep occurred, while an almost normal condition occurred in the pre-test sleep. Conclusion: During the 72-h sleep deprivation, no psycho-physiological stress was recorded. The participant has remained within the threshold of well-being. Only a peak was recorded during the 66th hour, but it was within the wellness threshold.