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Association analysis of the PTPN22 gene in childhood-onset systemic lupus erythematosus in Mexican population
2006
Genes and Immunity
Several studies have identified a functional single nucleotide polymorphism 1858C/T in the PTPN22 gene to be associated with several autoimmune diseases. Association studies of this polymorphism with familial and sporadic systemic lupus erythematosus (SLE) have shown some discrepancies. To our knowledge, this is the first study that includes only pediatriconset SLE patients. We performed a case-control association study in 250 unrelated Mexican patients with childhood-onset SLE consisting of
doi:10.1038/sj.gene.6364350
pmid:17066073
fatcat:bmbgvhdm7jgelekcyxdljdebgq