STUDY OF HORMONE RECEPTOR STATUS IN CARCINOMA BREAST
English

Kiran Somani, Abhishek Kansal, Raghvendra Singh, Akhilesh Patel, Sanjay Datey
2018 Journal of Evolution of Medical and Dental Sciences  
at Sri Aurobindo Institute of Medical Sciences, whereby 50 consecutive patients of diagnosed carcinoma of breast were admitted in the Department of General Surgery. A detailed clinical history was taken and thorough clinical examination was done and was subjected to surgery (Modified Radical Mastectomy) after routine investigations. The specimen sent for histopathology examination along with ER/PR/HER-2 receptor analysis by immunohistochemistry. The collected data was tabulated and analysed by
more » ... sing simple statistical methods. RESULTS In the present study, all 50 patients were female and the mean age of patients was 49.88, ranging from 21 to 78 years. 48% were pre-menopausal and 54% were post-menopausal. Right sided carcinoma breast was seen in 62% patients with upper outer quadrant lesions in 54% patients. Multicentric carcinoma was found in 6% patients. 40% patients were in stage 2B, 22% in stage 2a, 28% in stage 3a, 8% in stage 3b and 2% in stage 3c according to TNM staging. ER receptor was positive in 62% patients, PR receptor was positive in 54% of patients. HER-2 receptor was positive in 48% patients. Triple negative disease in 26% of patients. Infiltrating ductal carcinoma was found in 76% patients and 18% had intraductal carcinoma. We found 3 patients with lobular carcinoma.
doi:10.14260/jemds/2018/936 fatcat:zmkm6i4hinbxxmbojfu32ixjj4