An experimental study on microcholangiographic manifestation in extrahepatic bile duct obstruction

Y Lee, H S Kang, J H Park, C W Kim
1987 Journal of the Korean Radiological Society  
Microcholangiography using mi crobariu 버 was done for radiological observation of the morphology of intrahepatic microbiliary system and its change after extrahepatic bile duct obstruction. Regurgitation of microbarium into the system ic circulation was also observed Extrahepatic bile ducts of 40 rabbits were ligated and microcholangiography was done ju st after ligation, after 1 day, 3 days and 5 days. Inj ection pressure of microbarium was 58cm H 2 0 in 20 rabb its and 93cm H2 0 in another 20
more » ... rabbits Histologic findings of th e li ve r was compared with microcholangiographic find in gs The results were as follows 1. In microcholangiography, interlobular bil e ducts and ductules we re well noted, but bile cana li cu li we re not visibl e 2. After extrahepatic bile duct ligation, ductules and sma ll interlobular bile ducts we re tortuously d ilated and proliferated. These find ings progressed acco rdin g as the time after extrahepatic bil e duct ligation espec iall y between 1 and 2 days. 3. Microbarium was regurgitated into hepatic sinusoids from a portal tract due to rupture of interlobular bile ducts or ductules, and this was observed on ly in limited portions of sample tissue sections, but co uld be found in most of 40 rabbits From the above results, the morphology of intrahepatic microbiliary system and its change after extrahepatic bile duct obstruction cou ld be radiologicall y observed with microcholangiography, so this technique co uld be used for an experim enta l study about th e b iliary system * 본 논문은 한국땅사선연구재단의 보초로 이 루어진 것임.
doi:10.3348/jkrs.1987.23.1.1 fatcat:f7cp36ajinfvdb2ir3goa4wpiu