Enzymatische Hydroxylierung von Ruthenocen und Osmocen durch Leber-Mikrosomen / Enzymatic Hydroxylation of Ruthenocen and Osmocene

Michael Schneider, Martin Wenzel, Gerd Schachschneider
1982 Zeitschrift für Naturforschung C - A Journal of Biosciences  
In buffer solution (pH 7,4) ruthenocene and osmocene are far more stable than ferrocene. The metallocenes ruthenocene and osmocene are metabolized by microsomes of mouse liver in the presence of NADPH and O2. The KM-values are similar for both metallocenes, the rate of metabolism is higher for osmocene that for ruthenocene.
doi:10.1515/znc-1982-1-225 fatcat:agaex2ytgvd4vkmoi4zzuswj3q