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The work presented in this paper addresses the issues of fault detection and isolation properties of the partial PCA method and the isolation-enhanced PCA method. In order to increase the sensitivity of the residuals with respect to various faults, the structured residuals generated from both partial PCA and isolation-enhanced PCA are optimized. For the residual evaluation, the bootstrap technique is combined with the CUSUM method to achieve fast and robust detection. Three sensor faults anddoi:10.1016/j.chemolab.2008.03.003 fatcat:cpr26skblfbotgnjx47v4hxncu