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Super‐resolution imaging of highly curved membrane structures in giant vesicles encapsulating molecular condensates
2021
Advanced Materials
Molecular crowding is an inherent feature of cell interiors. Synthetic cells as provided by giant unilamellar vesicles (GUVs) encapsulating macromolecules (polyethylene-glycol and dextran) represent an excellent mimetic system to study membrane transformations associated with molecular crowding and protein condensation. Similarly to cells, such GUVs exhibit highly curved structures like nanotubes. Upon liquid-liquid phase separation their membrane deforms into apparent kinks at the contact line
doi:10.1002/adma.202106633
pmid:34710248
fatcat:5hhmxans2rbhreabue4l3tbqdm