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DISSOLUTION PROFILE STUDIES FOR RAMIPRIL AND LERCANIDIPINE FIXED-DOSE COMBINATION
2019
Drug development & registration
Preserved Fulltext
This article describes the results of the development of composition and technology of a combined drug, containing lercanidipine and ramipril, affording equivalent dissolution kinetics with original drugs. The comparative release profiles of the active pharmaceutical ingredients are shown. The choice of a solid dosage form in the form of bi-layer tablets was substantiated.
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