Studies on the Antitumor Active Polysaccharides from the Mycelia of Poria cocos WOLF. II
ブクリョウ菌糸体の抗腫瘍性多糖に関する研究 (第2報)

HISANORI KANAYAMA, NORIHIKO ADACHI, YOSHIKAZU FUKAI, IKUE TAKEUCHI, MASATOSHI TOGAMI
1986 Yakugaku zasshi  
Structural analysis was made on the glucan moiety of purified antitumor active polysaccharide fraction H11 obtained from the mycelia of P. cocos. In the 13C-nuclear magnetic resonance spectrum of fraction H11, signals at 102.9 and linked D-glucosyl redidues, respectively. On addition of NaOD solution, the C-1 signal was separated into two signals at 104.2 and 104.8 ppm which can be assigned to the C-1 filtration method with CPG-1000A. Complete methylation and hydrolysis of fraction H11 gave
more » ... 6-tri-, 2,3,4-tri-, 2,4-di-, and 2,3,4,6-tetra-0-methyl glucose as alditol acetates in a molar ratio of 3.96: 0.95: 1.05: 1.00. From these results, it has been revealed that fraction H11 is a highly branched (1,3)-
doi:10.1248/yakushi1947.106.3_206 fatcat:z2xaibolnba6znnykfaxpaz2ee