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Synopsis Attempts were made to prevent methylcholanthrene tumorigenesis in mice by immunization with the insoluble lipoprotein of methylcholanthrene-induced sarcomas of the same strain of mice. Swiss/Mk mice were intensively immunized with the insoluble lipoprotein fraction extracted by the Thomas method or with the supernatant fraction of isogenic methylcholanthrene-induced tumor cells, or normal cells with Freund adjuvant. As control groups, mice pretreated with Freund adjuvant alone anddoi:10.20772/cancersci1959.58.3_203 fatcat:5n236t7htbg3ri2punmzriq3da