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The human mutation rate per generation estimated from trio sequencing has revealed an almost linear relationship with the age of the father and the age of the mother. The yearly trio-based mutation rate estimate of ~0.43e-9 is markedly lower than prior indirect estimates of ~1e-9 per year from phylogenetic comparisons of the great apes. This suggests either a slowdown over the past 10 million years or an inaccurate interpretation of the fossil record. Here we use sequencing of chimpanzee,doi:10.1101/287821 fatcat:7h4m47g6gjeaflko6qbqzmjkvi