Our study plan was approved by Ethical Committee of our institute 80 patients were included in this study who underwent gastrointestinal anastomosis whether elective or emergency irrespective of age and gender. A detailed history and relevant preoperative investigation like complete blood picture, liver function test, kidney function test, electrolyte were taken and intra-operative information was collected like peritoneal cavity contaminated or non-contamination, technique of anastomosis and

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... dication of gastrointestinal anastomosis as well as post-operative information were also collected like pelvic collection wound dehiscence, burst abdomen, fecal discharge from the wound site. All these data were compared and analyzed with respect to their effect on the healing of wound and gastrointestinal anastomosis. The result revealed that age<20years, gender and technique, elective or emergency gastrointestinal anastomosis, diabetes mellitus, and tuberculosis had no effect on the healing of wound and gastrointestinal anastomosis whereas >60 years of age anaemia, hypoprotenemia, hyperbilirubin and malignancy, uremia and peritoneal contamination had impaired the healing of wound and anastomotic leak and there were statistically significant P value 0.04, 0.05, 0.04, 0, 05, 0.05, 0.04, 0.04. 0.003 Respectively.