Adaptations to day-night environmental changes are a prerequisite for survival in biological systems. In mammals this task is fulfilled by a photoneuroendocrine system which is comprised of 3 elements, the photosensitive retina, an endogenous oscillator in the hypothalamus, the suprachiasmatic nucleus (SCN) and neuroendocrine 197 12 Changes of the sensory airway innervation in actively sensitised and challenged guinea pigs. Neuropeptides such as tachykinins (Substance P [SP] and Neurokinin

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... ]) and Calcitonin Gene-Related Peptide (CGRP), which are released from sensory nerves fibres, are believed to be involved in the pathogenesis of inflammatory airway diseases, e.g. bronchial asthma. In order to evaluate D. 24 Glycoconjugate expression during hyaline cartilage development in the rat. Alterations in the expression of glycoconjugates during cartilage development in the chondrocranium, nasal skeleton, Meckel's cartilage, limb buds, vertebral bodies,