Tuberculosis (TB) is a direct infectious disease caused by Mycobacterium tuberculosis. Most of the TB germs attack the lungs, but they can also affect other organs. From the health profile data in Lhoong Community Health Center (CHC) in 2015 there were 5 pulmonary tuberculosis cases, while in 2016 there were 13 pulmonary TB cases. Aim: This study aims to determine the correlation between ventilation, lighting, humidity, occupancy density, type of floor and house temperature with the incidence

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... pulmonary tuberculosis in the work area of Lhoong CHC Aceh Besar District in 2018. Methods: This was an observational study with case control design. The total samples were 39 people including 13 case samples plus 26 control samples during 2018. Data for the independent variables were obtained by questionnaire, observation and measurement. Data analysis used chi square. Results: Bivariate analysis resulted that ventilation, lighting, occupancy density, humidity, and type of floor were related to the incidence of pulmonary TB in the work Area of Lhoong CHC, Aceh Besar District. The multivariate analysis resulted that occupancy density (OR= 30.8; 95%CI= 2.8-336.4) and ventilation (OR= 17.2; 95%CI= 1.6-178.9) were the most risk factors of pulmonary TB. Conclusions: Occupancy density and ventilation were the most risk factors of pulmonary TB in the work area of Lhoong CHC Aceh Besar District in 2018.