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Synthesis and properties of a novel pH sensitive poly(N-vinyl-pyrrolidone-co-sulfadiazine) hydrogel
eXPRESS Polymer Letters
Sulfadiazine monomer (SDM) was synthesized by the reaction of sulfadiazine with acryloyl chloride. The SDM was characterized by 1 H-NMR and IR spectra. A novel hydrogel with -SO2NH-group was obtained by the radical copolymerization of SDM with N-vinyl-pyrrolidone (NVP). Effects of the reaction temperature, reaction time, the monomer ratio, and the amount of the cross-linker on the pH sensitivity of the hydrogel were investigated. Results indicate that the hydrogel shows strong pH sensitivity indoi:10.3144/expresspolymlett.2007.26 fatcat:367m2hqqgbcdnpjizinsqmgrfi