A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is
Clinical & Experimental Thrombosis and Hemostasis
Megakaryocytes (MKs) are differentiated through linage commitment from hematopoietic stem cells and terminally differentiated MKs release platelets. The processes of megakaryopoiesis and subsequent thrombopoiesis are unique and complex. The underlying mechanisms of MK development and platelet production, beginning with stem cells, are not fully understood because of the difficulty in obtaining suf ficient numbers of MKs for analysis. However, recent advances in cell biology have furthereddoi:10.14345/ceth.14014 fatcat:etuo22gf5veftcyl63mf7tphlq