Clinical Practice of Unsedated Colonoscopy Among the Liver Transplant Recipients [post]

2019 unpublished
The incidence of colorectal cancer was increased in the liver transplant recipients and clinical practice of unsedated colonoscopy among the liver transplant recipients hasn't been fully studied. Our prospective and observational study was conducted in a tertiary hospital to investigate the clinical practice of unsedated colonoscopy among the liver transplant recipients. Methods: Between June 2017 and June 2018, clinical data of the 72 liver transplant recipients received the screening
more » ... screening colonoscopy conducted by a same endoscopists was collected. And a group of asymptomatic health examiner of same age and same gender was chosen as control group at a ratio of 1:3. Data of the colonoscopy performance, patient satisfaction and colonoscopy finding were compared between the two groups. Results: No difference was observed between the two groups in the bowel clearance ( P =0.273) , however, cecal intubation time was longer ( P =0.024) and the auxiliary abdominal compression by nurses was more frequent ( P 0.01) in liver transplantation group. In term of patient's satisfaction, postprocedural visual analog scale, the willingness of repeat the same procedure and the four-point Likert scale (no pain, slight pain, moderate pain, severe pain) on the second day were comparable between the two groups. Compared with control group, the incidence of polyps was higher in the liver transplantation group (50.00% (36/72) vs37.04% (80/216), P =0.036), and the incidence of adenomatous polyps(33.33%vs 24.07%, P =0.084) and advanced polyps (11.11%vs 5.56%, P =0.094) were also higher in the liver transplantation group, but no statistical difference was observed. Conclusions: Liver transplantation mildly increases the difficulty of colonoscopy with experienced practitioners, although the patient's satisfaction was comparable with the common people.
doi:10.21203/rs.2.19615/v1 fatcat:w3glzj6uuffjfpwzdylfhm42le