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Keywords: single giant unilamellar vesicle, alamethicin channel, bovine serum albumin, avidin slip A single giant unilamellar vesicle (GUV) functionalized with an anti-bovine serum albumin (BSA) antibody was immobilized on an avidin slip, and alamethicin channels were embedded as a signal transduction element for creating a channel-based molecular sensing system. The GUV sensor based on the membrane-bound anti-BSA antibody receptor exhibited alamethicin activities that reflected the binding ofdoi:10.18494/sam.2021.3067 fatcat:kvz5uikg7fgfvbk2wztckayokm