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Mechanisms of Bacterial Transcription Termination: All Good Things Must End
Annual Review of Biochemistry
Transcript termination is essential for accurate gene expression and the removal of RNA polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are responsible for proper transcript termination: intrinsic termination and Rho-dependent termination. Intrinsic termination is mediated by signals directly encoded within the DNA template and nascent RNA, whereas Rho-dependent termination relies upon the adenosine triphosphate-dependent RNA translocase Rho, which bindsdoi:10.1146/annurev-biochem-060815-014844 pmid:27023849 fatcat:on54etg65fhgve6fkgauykspia