The Litsea floribunda Gamble was widely used for various medicinal purposes. The present study was aimed to screening the phytochemicals presentin theleaf and bark extract of L. floribunda and also assess their antioxidant and anti-inflammatory properties. The results revealed that the leaf and bark extract showed the extracts are rich in phytomoleculeslikephenolics and tannin. The leaf extract showed more antioxidant activitiessuch as total antioxidant, ABTS, superoxide radical scavenging,

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... , and DPPH reducing power activities were done respectively. Better radical activities Albumin denaturation and Anti-proteinase were observed in leaf extractthan in the bark extract, also it showed significant anti-inflammatory activities. Finally, L. floribunda could be considered as the most valuablealternative medicinalsource for many diseases.