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Identification of Key Genes for Nasopharyngeal Carcinoma by Gene Expression and DNA Methylation Data Integration Analysis
Background: The pathogenesis of Nasopharyngeal carcinoma (NPC) is very complicated. The present study aimed to identity some candidate genes as biomarkers for NPC diagnosis and pathogenesis.Methods: Three Microarray datasets GSE53819, GSE64634 and GSE12452 and a methylation array (GSE52068) were re-analyzed. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of the differentially expressed genes (DEGs) were applied. STRING software was used todoi:10.21203/rs.3.rs-96113/v1 fatcat:qaya6k5scrbxhobpwouhpgjkou