Hepatocyte Nuclear Factor-4α Is Essential for Glucose-stimulated Insulin Secretion by Pancreatic β-Cells

Atsuko Miura, Kazuya Yamagata, Masafumi Kakei, Hiroyasu Hatakeyama, Noriko Takahashi, Kenji Fukui, Takao Nammo, Kazue Yoneda, Yusuke Inoue, Frances M. Sladek, Mark A. Magnuson, Haruo Kasai (+3 others)
2005 Journal of Biological Chemistry  
2 The abbreviations used are: HNF, hepatocyte nuclear factor; RT, reverse transcription; BSA, bovine serum albumin; WT, wild type; KO, knock out; MODY1, maturity-onset diabetes of the young; PPAR, peroxisome proliferator-activated receptor; VDCC, voltage-dependent calcium channel; SHP, small heterodimer partner.
doi:10.1074/jbc.m507496200 pmid:16377800 fatcat:ct2buhshtvcmllr5bwjvdgopgm