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Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction
2003
Cancer Epidemiology, Biomarkers and Prevention
Individuals with cytological atypia in sputum may be at increased risk for lung cancer. We conducted a longitudinal analysis of the association between lung cancer incidence and cytological atypia in sputum samples collected prospectively from an ongoing cohort of adults at high risk for lung cancer. Cohort members had a smoking history of > or = 30 pack-years and chronic obstructive pulmonary disease documented by pulmonary airflow testing. Sputum samples collected at baseline and periodically
pmid:14578133
fatcat:miexn24rffemdb5ti2y5ztum2q