Antibodies against 1940s era a/H1N1 influenza strains a/Weiss/43 and a/FM/1/47 and heterotypic responses after seasonal vaccination of an elderly Spanish population

Ivan Sanz, Silvia Rojo, Sonia Tamames, Jose María Eiros, Raúl Ortiz de Lejarazu
2018 Immunity & Ageing  
and methods: Elderly people have experienced several influenza natural infections and seasonal vaccinations during their lives. The aim of this work was to evaluate in an elderly Spanish population the presence of antibodies (Abs) against some 1940s era A/H1N1 influenza viruses and some new influenza viruses. We also evaluated the homologous and heterotypic responses after seasonal influenza vaccination. We collected pre-and post-vaccination serum samples from 174 elderly people (≥65 years) who
more » ... ple (≥65 years) who were vaccinated with seasonal influenza vaccines during the
doi:10.1186/s12979-018-0116-9 fatcat:chbtwqcikrgodkjy2xb475fcwm