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Optimal Impulsive Control With Application to Antiangiogenic Tumor Therapy
2018
IEEE Transactions on Control Systems Technology
An optimal control algorithm is proposed for impulsive differential systems, i.e. systems evolving according to ordinary differential equations between any two control actions, occurring impulsively at discrete time instants. Measurements are as well acquired at discrete time instants. The model-based control law is conceived for medical and health-care frameworks and, indeed, is applied to synthesize a feedback antiangiogenic tumor therapy. To cope with unavailable or temporally sparse
doi:10.1109/tcst.2018.2861410
fatcat:askgjbm5pfcvbjfk7n7k3wap6e