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Cholesterol, Oxysterols and LXRs in Breast Cancer Pathophysiology
2020
International Journal of Molecular Sciences
Breast cancer is the most frequent cancer among women. In 2018, it is estimated that 627,000 women died from breast cancer. This is approximately 15% of all cancer deaths among women (WHO 2018). Breast cancer is a multifactorial chronic disease. While important progress has been made to treat patients, many questions regarding aspects of this disease relating to carcinogenesis are still open. During carcinogenesis, cells exhibit cholesterol homeostasis deregulation. This results in an
doi:10.3390/ijms21041356
pmid:32079340
pmcid:PMC7072989
fatcat:ehsrfjyehzbwdb5fgld3g7wtf4