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Marine halophytes are an outstanding reservoir of natural products and several species have anti-infectious traditional uses. However, little is known about their potential against neglected tropical ailments, such as Chagas disease. This work evaluated for the first time the in vitro anti-Trypanosoma cruzi activity of extracts from the aromatic and medicinal species Helichrysum italicum subsp. picardii (Boiss. & Reut.) Franco (Asteraceae, everlasting) and Crithmum maritimum L. (Apiaceae, seadoi:10.21203/rs.3.rs-129046/v1 fatcat:okfemgvv5nfpznw2mlzcjkm5su