Evaluation of Intracranial Pressure-Regulation by MRI-measured Cerebrospinal Fluid Pulsation

Masatomo UEHARA, Tosiaki MIYATI, Naoki OHNO, Riho OKAMOTO, Mitsuhito MASE
Medical Imaging and Information Sciences  
We determined cerebrospinal fluid (CSF) stroke volume under different intracranial pressure with individuals in the supine and sitting postures where intracranial pressure drops using an original MRI system called "Gravity MRI" that can obtain images in any posture. On a 0.4-T Gravity MRI, ECG-synchronized 2D phase contrast cine MRI technique was used to measure the flow velocity of CSF at the boundary between cranial and spinal cavities (mid-C2 level) and the cerebral aqueduct in the supine
more » ... sitting postures. We obtained the CSF stroke volume from phase-mapped velocity images over the cardiac cycle in seven healthy volunteers and compared those between supine and sitting postures. The CSF stroke volume at the mid-C2 level in the sitting posture was significantly lower than that in the supine posture, whereas the CSF stroke volume at the cerebral aqueduct did not significantly differ between both postures. There was no significant correlation in the rate of change in the CSF stroke volume at the mid-C2 level and the cerebral aqueduct. In the evaluation of intracranial pressure-regulation function using CSF pulsation, a cross-section at the mid-C2 level is more desirable than at the cerebral aqueduct.
doi:10.11318/mii.36.156 fatcat:f6u3a23zjvgffiryxr3ubbs5ti