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e0159 Osteopontin is involved in urotensin II induced migration of adventitial fibroblasts from rat aorta
2010
Heart
Preserved Fulltext
a dose-dependent and time-dependent manner, with maximal effect at a concentration of 10 À8 mol/l at 12 h (in the level of protein secretion from the cells, p<0.01) or 24 h (in the level of protein expression in the cells, p<0.01), which could also be inhibited by these inhibitors (p<0.01 in all groups). Conclusion Urotensin II may stimulate the expression of monocyte chemoattractant protein-1 in rat aortic adventitial fibroblasts, through its receptor and the Ca 2+ channel, protein kinase C,
doi:10.1136/hrt.2010.208967.159
fatcat:n5wsvwxdfbge3lvgzpmobopyie