ProtVista: visualization of protein sequence annotations

Xavier Watkins, Leyla J Garcia, Sangya Pundir, Maria J Martin, Alfonso Valencia
2017 Bioinformatics  
ProtVista is a comprehensive visualization tool for the graphical representation of protein sequence features in the UniProt Knowledgebase, experimental proteomics and variation public datasets. The complexity and relationships in this wealth of data pose a challenge in interpretation. Integrative visualization approaches such as provided by ProtVista are thus essential for researchers to understand the data and, for instance, discover patterns affecting function and disease associations.
more » ... bility and Implementation: ProtVista is a JavaScript component released as an open source project under the Apache 2 License. Documentation and source code are available at http://ebi-uni prot.github.io/ProtVista/. Contact: martin@ebi.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online. Visualization ProtVista's display consists of three sections (see Fig. 1 ). The first, located at the top, is used for navigation and zooming. It represents the full length of the protein sequence. Elements on both sides of the component can be dragged to specify the zoom level, as well as navigating along the sequence. The second section, on the left, consists of categories of the feature types. The third and main section of the visualization is the area where the features are displayed in tracks. Each category track is collapsed by default, providing a feature-
doi:10.1093/bioinformatics/btx120 pmid:28334231 pmcid:PMC5963392 fatcat:fzl2glx3tvgqpjs5amex7y6rl4