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Formulation Design and Development of Self-Nanoemulsifying Drug Delivery Systems Containing a Hydrophobic Selective β1-Adrenoreceptor Blocker
The present work was aimed to design and develop self-nanoemulsifying drug delivery systems (SNEDDS) with the objective to overcome the problems associated with the delivery of talinolol, a hydrophobic and poorly bioavailable drugs having pH dependant solubility. The solubility of talinolol in various oils, surfactants, co-surfactants and aqueous phases were determined to identify and select the best combination with proper dose incorporation. Various surfactants and co-surfactants werefatcat:wmt4qv7kizehhil44eiqfd6pga