Objective: To find out various clinical patterns of ACDR (Adverse Cutaneous Drug Reaction) due to NSAIDS, the most common NSAIDS responsible for it. Materials and method: The study was cross sectional and was carried out in the department of dermatology in a teaching institute at a rural based tertiary care centre of Gujarat Results: A total of 288 patients enrolled in the study, among which 173 (60.07%) were males and 115 (39.93%) were females. Most common age group was 21-40 years. Most

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... presenting complaint was redness (which was generalized in some and localized in few) in 61 (26.75%) patients followed by itching in 58 (25.43%) patients. With most common diagnosis of cutaneous ADR were urticaria 97(33.6%), angioedema 45(15.6%), FDR (Fixed Drug Reaction) 17(5.9%), DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) 11(3.8%), SJS(Stevenson Johnson Syndrome) 9(3.1%), TEN (Toxic Epidermal Necrolysis) 1(0.34%) and others 37(12.8%). Conclusion: Pharmacovigilance improves the recognition of ADRs and helps the medical professional to have safe practice.