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Skeletal muscle reaction to exercise is an essential are of research due to its ongoing prevalence in disease research and general health. It is well documented that under exercise conditions, biogenesis and autophagy increase. One main component of this pathway are lysosomes, the essential cellular clearance machine. Statistical analyses used to analyze these data have been sustained over the years. The objective of this systematic review is to compare and contrast the different methods useddoi:10.7287/peerj.preprints.556v1 fatcat:ma74z2pgenbohjf3fr5jsi622q