Use of Circulating and Cellular miRNAs Expression in Forensic Sciences

Raluca Dumache, Alexandru Florin Rogobete, Dorel Sandesc, Ovidiu Horea Bedreag, Veronica Ciocan, Camelia Muresan, Adrian Tudor Stan, Mihai Sandesc, Anca Dinu, Sonia Elena Popovici, Alexandra Enache
2017 Journal of Interdisciplinary Medicine  
The current practice in the field of forensic medicine imposes the use of modern investigation techniques. The complexity of laboratory investigation methods needed for a final result of the investigation in forensic medicine needed new biomarkers of higher specificity and selectivity. Such biomarkers are the microRNAs (miRNAs), short, non-coding RNAs composed of 19–24 nucleotides. Their characteristics, such as high stability, selectivity, and specificity for biological fluids, differ from
more » ... ue to tissue and for certain pathologies, turning them into the ideal candidate for laboratory techniques used in forensic medicine. In this paper, we wish to highlight the biochemical properties and the usefulness of miRNAs in forensic medicine.
doi:10.1515/jim-2017-0074 fatcat:sjgyt3k4ajbn7oclyk4jaaddua