Giant cell tumor remains one of the most controversial and discussed bone tumors. Its diagnosis may be very difficult especially in vertebral localization as it requires a careful study of the pathology tissue. The authors report a series of four patients, treated in the MT Kassab orthopaedic Institute for vertebral giant cell tumor (GCT), with different clinical presentation and therapeutic strategies. By presenting those cases we point to surgical and medical treatments' difficulties and the

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... hallenge of avoiding local recurrence and distant metastasis of this tumor.