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Formulation and Evaluation of Mouth Dissolving Film of Prochlorperazine Maleate
Journal of Drug Delivery and Therapeutics
This research work was aimed to enhance the oral bioavailability and provide faster onset of action of Prochlorperazine maleate (used for the treatment nausea and vomiting) by formulating its mouth dissolving film (MDF). Prochlorperazine belongs to BCS II and oral bioavailability of it's about 11-15%. The MDF of Prochlorperazine maleate was prepared by solvent casting method using HPMC (film forming agent),Glycerol (plasticizer), Betacyclodextrin (solubilizing agent), Citric acid (salivadoi:10.22270/jddt.v9i6.3679 fatcat:aun3t7lb3zdgbamcs4gxu5ywoq