Effects of haemodialysis on Hemoglobin and red cell indices in chronic kidney disease patients at a tertiary health care institute

Dr. Pradhiksha Dasaprakash, Dr. Shivashekar Ganapathy, Dr. Veena Raja
2019 International Journal of Clinical and Diagnostic Pathology  
Chronic kidney disease (CKD) is a global health problem, with very high cost of care and greater burden particularly in developing countries like India. Material and Method: This prospective observational study of effects on hemoglobin and red cell indices in CKD before and after hemodialysis conducted on 150 CKD patients in SRM Medical College Hospital & Research Centre. Results: The most frequent morphologic features were normochromic-normocytic (78.7%), microcytic hypochromic (14.7%),
more » ... tic (3.3%) and dimorphic (3.3.%). Haemoglobin (Hb) levels and platelets counts are significantly reduced in post dialysis with a mean level of Hb 8.7 when compared to pre dialysis mean value of 7.78g/dL. There was a significant increase in MCV, with decrease in MCH and MCHC in the post dialysis values compared to pre dialysis. Conclusion: These hematological abnormalities expose CKD patients to higher risk of anemia-related complications. The present investigation might help clinicians to initiate precautions before and after dialysis procedures.
doi:10.33545/pathol.2019.v2.i1b.18 fatcat:srpqni4gnnef3mfq2lpyxvbrdi