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Image guided external beam radiation therapy (EBRT) for the treatment of cancer enables accurate placement of radiation dose to the cancerous region. However, the deformation of soft tissue during the course of treatment, such as in cervical cancer, presents significant challenges. Furthermore, the presence of pathologies such as tumors may violate registration constraints and cause registration errors. In this paper, we present a unified MAP framework that performs automatic segmentation,pmid:21761683 pmcid:PMC3889153 fatcat:2xvvukdw6vehbjigc6535ph2gq