htsget: a protocol for securely streaming genomic data

Jerome Kelleher, Mike Lin, C H Albach, Ewan Birney, Robert Davies, Marina Gourtovaia, David Glazer, Cristina Y Gonzalez, David K Jackson, Aaron Kemp, John Marshall, Andrew Nowak (+5 others)
2018 Bioinformatics  
Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration.
doi:10.1093/bioinformatics/bty492 pmid:29931085 pmcid:PMC6298043 fatcat:slz7ksxtjffl5e7bnbfcj5t24m