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We present a novel level-set method for evolving open surfaces embedded in three-dimensional volumes. We adapt the method for statistical detection and segmentation of cytoarchitectonic regions of the cortical ribbon (e.g., Brodmann areas). In addition, we incorporate an explicit interface appearance model which is oriented normal to the open surface, allowing one to model characteristics beyond voxel intensities and high gradients. We show that such models are well suited to detecting embeddeddoi:10.1109/iccv.2007.4409138 dblp:conf/iccv/BoseFFHG07 fatcat:ploaggcvsnfsngqpsggmgfmb7m