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Patients with childhood cancer are at increased risk of developing melanoma as a secondary malignancy. It is unclear whether this risk is related to underlying patient predisposition or secondary to treatment effect. We report a case of a 43-year-old male with a history of childhood medulloblastoma at the age of 13 treated with surgery and craniospinal irradiation who presented with an enlarging occipital mass and contiguous, cutaneous, ulcerated nodule. The nodule appeared to arise within thedoi:10.5430/crcp.v3n1p43 fatcat:2p25pwrkv5hi3o6mdnpahl7dte