Nursing Process is a systematic problem-solving approach used to identify, prevent and treat actual or potential health problems and promote wellness. It has five steps-assessment, diagnosis, planning, implementation, and evaluation. Objective: To assess factors affecting implementation of nursing process among nurses in selected governmental hospitals from February-April, 2011 at Addis Ababa, Ethiopia. Method: A cross-sectional quantitative study was conducted on selected governmental

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... in Addis Ababa. Purposive sampling was used for selection of hospitals. Black Lion, St. Paul, Ras Desta Damitew Memorial, and Yekatit 12 hospitals were convenient for the study. The sample size was 202. Data was analyzed using SPSS 16th version. Result: Nurses working in a stressful working environment were 2.8 (adjusted OR: 0.357, 95%CI: (0.157-0.814)) times less likely to implement nursing process than disorganized working environment adjusting for facility accessibility, knowledge, and sex. Forty eight (25%) of respondents were anxious from high patient flow. Among those 15(31.3%), 22(45.8%), and 11(22.9%) have committed knowledge, executive, and slip/slap error respectively. Highly knowledgeable respondents were 38.913 (Adjusted OR: 38.913, 95%CI: (10.3-147.006) times more likely to implement nursing process than low knowledge group nurses adjusted for working environment, facility, and sex. Conclusion: The study has identified organizational factors, patient related factors, and level of knowledge and skill were among those factors highly influenced nursing process implementation. This factors cause poor quality of nursing care, disorganized caring system, conflicting role, medication error and readmission with similar problem, dissatisfaction with the care patients have received, and increased mortality.