N-Pyrrylarylsulfones with High Therapeutic Potential

Valeria Famiglini, Sabrina Castellano, Romano Silvestri
2017 Molecules  
This review illustrates the various studies made to investigate the activity of N-pyrrylarylsulfone containing compounds as potential antiviral, anticancer and SNC drugs. A number of synthetic approaches to obtain tetracyclic, tricyclic and non-cyclic compounds, and their biological activity with regard to structure-activity relationships (SARs) have been reviewed. The literature reviewed here may provide useful information on the potential of N-pyrrylarylsulfone pharmacophore as well as
more » ... concepts for the design and synthesis of new N-pyrrylarylsulfone based agents.
doi:10.3390/molecules22030434 pmid:28282943 fatcat:o773wq7unvexdmux4rmbfdf5eu