Mixed Connective Tissue Disease with Multiple Organ Damage. Successful Treatment with Plasmapheresis

Masato SEGUCHI, Yoshiyuki SOEJIMA, Akio TATEISHI, Hiroshi IIDA, Midori YAMAMOTO, Ken NAKASHIMA, Fujio MURAKAMI, Satomi OHASHI, Susumu YAMASHITA, Tsuyoshi MAEKAWA, Akihiro MURASHIGE, Seiji UMEMOTO (+2 others)
2000 Internal medicine (Tokyo. 1992)  
A 24-year-oId-woman with mixed connective tissue disease (MCTD)developed multiple organ failure, disseminated intravascular coagulation (DIC), metabolic addosis, and respiratory and renal failure resulting from visceral vasospasm, so-called visceral Raynaud's phenomenon. After plasmapheresis, the condition of multiple organ failure was markedly improved. The successful treatment with plasmapheresis was dependent upon the removal of immune complexes in serum and improvement of visceral
more » ... n. Thus plasma exchange is recommendedas a possible a treatment for multiple organ damagein MCTD.
doi:10.2169/internalmedicine.39.1119 fatcat:diszbsvy6zhxdpzhcp266x63hi