Raising Awareness of Non-Hodgkin Lymphoma in HIV-infected Adolescents

Paola Zangari, Veronica Santilli, Nicola Cotugno, Emma Manno, Giuseppe Palumbo, Alessandra Lombardi, Rita De Vito, Hyppolite Tchidjou, Stefania Baldassari, Paola Ariganello, Giuseppe Pontrelli, Francesca De Florio (+2 others)
2013 Journal of pediatric hematology/oncology  
Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the
more » ... , may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.
doi:10.1097/mph.0b013e318282cef5 pmid:23426000 fatcat:gmaqelgmobaptomb4h376fjxzy