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PO-187 Liquid-phase polarity facilitates attachment, adhesion and metastasis of tumour cells
Metastases and EMT
Introduction Breast cancer is amongst the most common types of cancer for women and the primary cause of cancer related death. The high mortality rates are due to the metastatic spread of cancer cells and tumour recurrence after therapy. Transferring their cargo from one cell to another, EVs (extracellular vesicles) are involved in maintaining homeostasis in normal physiology, but are deregulated in cancer. EVs have been shown to play particular roles in all hallmarks of cancer with great focusdoi:10.1136/esmoopen-2018-eacr25.229 fatcat:s4wx62oxgjhtdigaf3utgh6vxy